2-Naphthaldehyde
Based on 1 Customer Validation
2-Naphthaldehyde belongs to naphthalene-based bis-aromatic aldehyde compounds. 2-Naphthaldehyde scavenges DPPH and ABTS+ free radicals, and exerts reductive effects by donating hydrogen atoms to interrupt free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD+-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases.
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- Pureza : 99.80%
- No. CAS: 66-99-9
- Fòrmula: C11H8O
- Peso molecular:156.18
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-Y0075R
2-Naphthaldehyde (Standard)Reference Standard -
HY-W012657
4-EthylbenzaldehydeAnti-parasitic Agent -
HY-D0908
NinhydrinChromogenic Probe -
HY-D0165
NaphthoresorcinolDye -
HY-W005148
3-Amino-2-naphthoic acidBiochemical Reagent -
HY-W017588
N-(2-Hydroxyethyl)maleimideMaleimide-Based Spacer -
HY-125457
α-NaphtholbenzeinPH Indicator -
HY-W016103
1-Hydroxy-2-naphthoic acidBiochemical intermediate -
HY-W012657R
4-Ethylbenzaldehyde (Standard)Standard of 4-Ethylbenzaldehyde -
HY-W016187
2-(Naphthalen-2-yl)acetic acidPlant Growth Regulator -
HY-32126
1-FluoronaphthaleneOrganofluorine Compound -
HY-78494
1-Naphthaleneboronic acidBiochemical Reagent
Actividad biológica
Descripciòn
In Vitro
2-Naphthaldehyde (20 μM; varied concentrations) is efficiently oxidized by purified SALDH from Pseudomonas sp. strain C6, with an apparent Km of 3.5 μM, moderate substrate inhibition (Ki of 136 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 66-99-9
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Appearance Solid
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Peso molecular 156.18
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Fòrmula C11H8O
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Color Off-white to yellow
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SMILES
O=CC1=CC2=C(C=CC=C2)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 50 mg/mL (320.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[2]. Singh R, et al. Purification and characterization of NAD+ -dependent salicylaldehyde dehydrogenase from carbaryl-degrading Pseudomonas sp. strain C6. Applied biochemistry and biotechnology. 2014 Jan;172(2):806-19. [Content Brief]
[3]. Oladipo SD, et al. Antidiabetes and antioxidant potential of Schiff bases derived from 2-naphthaldehye and substituted aromatic amines: Synthesis, crystal structure, Hirshfeld surface analysis, computational, and studies. Heliyon. 2024 Jan 15;10(1):e23174. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4029 mL | 32.0143 mL | 64.0287 mL | 160.0717 mL |
| 5 mM | 1.2806 mL | 6.4029 mL | 12.8057 mL | 32.0143 mL | |
| 10 mM | 0.6403 mL | 3.2014 mL | 6.4029 mL | 16.0072 mL | |
| 15 mM | 0.4269 mL | 2.1343 mL | 4.2686 mL | 10.6714 mL | |
| 20 mM | 0.3201 mL | 1.6007 mL | 3.2014 mL | 8.0036 mL | |
| 25 mM | 0.2561 mL | 1.2806 mL | 2.5611 mL | 6.4029 mL | |
| 30 mM | 0.2134 mL | 1.0671 mL | 2.1343 mL | 5.3357 mL | |
| 40 mM | 0.1601 mL | 0.8004 mL | 1.6007 mL | 4.0018 mL | |
| 50 mM | 0.1281 mL | 0.6403 mL | 1.2806 mL | 3.2014 mL | |
| 60 mM | 0.1067 mL | 0.5336 mL | 1.0671 mL | 2.6679 mL | |
| 80 mM | 0.0800 mL | 0.4002 mL | 0.8004 mL | 2.0009 mL | |
| 100 mM | 0.0640 mL | 0.3201 mL | 0.6403 mL | 1.6007 mL |
2-Naphthaldehyde Related Classifications
HY-Y0075 Related Classifications
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