4-Hydroxytryptophol
4-Hydroxytryptophol is an in vitro metabolite of psilocin, can be found in human liver microsomes and recombinant monoamine oxidase A systems. 4-Hydroxytryptophol is not detected in in vivo samples from mice or humans.
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- No. CAS: 1379213-90-7
- Fòrmula: C10H11NO2
- Peso molecular:177.20
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
4-Hydroxytryptophol is produced in minor amounts (43.4 nM) alongside a 29% decrease in psilocin concentration when 1,000 nM psilocin is incubated with human liver microsomes for 240 minutes[1].
4-Hydroxytryptophol is produced in minor amounts (16.9 nM) without a visible decrease in psilocin concentration when 1,000 nM psilocin is incubated with recombinant MAO-A enzymes for 300 minutes[1].
4-Hydroxytryptophol shows no relevant binding affinity to human 5-HT1A, 5-HT2A, and 5-HT2C receptors (Ki > 10,000 nM) in HEK 293 cell line membrane preparations[1].
4-Hydroxytryptophol shows no relevant activation potency at human 5-HT1A, 5-HT2A, and 5-HT2B receptors (EC50 > 10,000 nM) in NIH/3T3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1379213-90-7
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Peso molecular 177.20
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Fòrmula C10H11NO2
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SMILES
OC1=CC=CC2=C1C(CCO)=CN2
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Synonyms
4-HTP
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)