4E1RCat 17d
4E1RCat 17d is a derivative of the ATG5 inhibitor lead compound T1742 (HY-183807). 4E1RCat 17d shows no activity against the interactions of ATG5-ATG16L1 and ATG5-TECAIR. 4E1RCat 17d induces Autophagy inhibition.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2841473-92-3
- Fòrmula: C31H24N2O5
- Peso molecular:504.53
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
4E1RCat 17d (Compound 17d) shows no obvious inhibitory activity against the ATG5−ATG16L1 and ATG5−TECAIR interactions in a cell-free HTRF binding assay[1].
4E1RCat 17d (20 μM; 6 h) inhibits autophagy in COS-7 cells, reducing autophagy incidence to 20.01%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:COS-7 cells
-
Concentration:20 μM
-
Incubation Time:6 h
-
Result:Reduced autophagy incidence in COS-7 cells to 20.01%.
Chemical Information
-
No. CAS 2841473-92-3
-
Peso molecular 504.53
-
Fòrmula C31H24N2O5
-
SMILES
CC(NC1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=C1)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz