FBPase-IN-5
Based on 1 Customer Validation
MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.31%
- No. CAS: 882755-95-5
- Fòrmula: C12H15N2O5PS
- Peso molecular:330.30
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
IC50: 31 nM (human), 121nM (monkey), and 189 nM (rat) [1] .
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | EC50 |
140 nM
Compound: MB07729
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Inhibition of glucose production in human hepatocyte assessed as reduction in blood glucose level
Inhibition of glucose production in human hepatocyte assessed as reduction in blood glucose level
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[PMID: 29055870] |
Chemical Information
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No. CAS 882755-95-5
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Appearance Solid
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Peso molecular 330.30
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Fòrmula C12H15N2O5PS
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Color White to off-white
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SMILES
CC(C)(C)C(C1=C(C2=CC=C(P(O)(O)=O)O2)N=C(N)S1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FBPase-IN-5 Related Classifications
HY-16308 Related Classifications
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