Amilo-5MER
Based on 1 publication(s) in Google Scholar
Amilo-5MER (5-MP) is an orally active and selective Serum Amyloid A (SAA) inhibitor. Amilo-5MER specifically inhibits the release of pro-inflammatory cytokines IL-6 and IL-1β from SAA-activated cells. Amilo-5MER reduces chronic inflammation and relieves symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS). Amilo-5MER is promising for research of autoimmune diseases and chronic inflammatory diseases.
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- No. CAS: 1860001-61-1
- Fòrmula: C23H40N6O9S
- Peso molecular:576.66
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1860001-61-1
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Peso molecular 576.66
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Fòrmula C23H40N6O9S
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Synonyms
5-MP
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Sequence
Ac-Met-Thr-Ala-Asp-Val-NH2
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Sequence Shortening
Ac-MTADV-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury. [Abstract]2026 Jun;13(34):e22891. PMID: 41904943
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Amilo-5MER Related Classifications
HY-P10935 Related Classifications
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