AP23848
AP23848 is an ATP-dependent kinase inhibitor that effectively and selectively targets the Kit activation loop mutation both in vitro and in vivo, showing anti-tumor activity. AP23848 can inhibit the phosphorylation of the activated Kit mutation and tumor growth in mice, making it suitable for targeting diseases with the D816V mutation, such as systemic mastocytosis (SM) and acute myeloid leukemia (AML) research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 834894-21-2
- Fòrmula: C30H38N5O2P
- Peso molecular:531.63
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 834894-21-2
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Peso molecular 531.63
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Fòrmula C30H38N5O2P
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SMILES
OC1=CC=CC(CCN2C3=NC(C4CCCC4)=NC(NC5=CC=C(P(CCC)(CCC)=O)C=C5)=C3N=C2)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)