APL-1092
APL-1092 (Mal-Exo-EEVC-Exatecan) is a drug-linker conjugate for ADC, which contains Exatecan (HY-13631) (ADC payload) and a linker.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2921735-91-1
- Fòrmula: C65H77FN12O19
- Peso molecular:1349.37
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Almacenamiento:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Chemical Information
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No. CAS 2921735-91-1
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Appearance Solid
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Peso molecular 1349.37
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Fòrmula C65H77FN12O19
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SMILES
O=C(C=CC1=O)N1CCCCCNC(C(C2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)=O)OC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O
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Synonyms
Mal-Exo-EEVC-Exatecan
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvente y solubilidad
DMSO : ≥ 100 mg/mL (74.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7411 mL | 3.7054 mL | 7.4109 mL | 18.5272 mL |
| 5 mM | 0.1482 mL | 0.7411 mL | 1.4822 mL | 3.7054 mL | |
| 10 mM | 0.0741 mL | 0.3705 mL | 0.7411 mL | 1.8527 mL | |
| 15 mM | 0.0494 mL | 0.2470 mL | 0.4941 mL | 1.2351 mL | |
| 20 mM | 0.0371 mL | 0.1853 mL | 0.3705 mL | 0.9264 mL | |
| 25 mM | 0.0296 mL | 0.1482 mL | 0.2964 mL | 0.7411 mL | |
| 30 mM | 0.0247 mL | 0.1235 mL | 0.2470 mL | 0.6176 mL | |
| 40 mM | 0.0185 mL | 0.0926 mL | 0.1853 mL | 0.4632 mL | |
| 50 mM | 0.0148 mL | 0.0741 mL | 0.1482 mL | 0.3705 mL | |
| 60 mM | 0.0124 mL | 0.0618 mL | 0.1235 mL | 0.3088 mL |
APL-1092 Related Classifications
HY-169324 Related Classifications
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