AT-076
AT-076 is an opioid pan antagonist at nociception, kappa, mu, and delta opioid receptors, with Ki values of 1.75 nM (NOP), 1.67 nM (MOP), 1.14 nM (KOP) and 19.6 nM (DOP), respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1657028-64-2
- Fòrmula: C26H35N3O3
- Peso molecular:437.57
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Opioid Receptor
More
Actividad biológica
|
NOP Receptor/ORL1 1.75 nM (IC50) |
μ Opioid Receptor/MOR 1.67 nM (IC50) |
κ Opioid Receptor/KOR 1.14 nM (IC50) |
δ Opioid Receptor/DOR 19.6 nM (IC50) |
Chemical Information
-
No. CAS 1657028-64-2
-
Peso molecular 437.57
-
Fòrmula C26H35N3O3
-
SMILES
OC1=CC=CC(C(CC2)CCN2C[C@H](C(C)C)NC([C@H]3CC4=CC=C(O)C=C4CN3)=O)=C1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Nurulain T Zaveri, et al. Discovery of the first small-molecule opioid pan antagonist with nanomolar affinity at mu, delta, kappa, and nociceptin opioid receptors. ACS Chem Neurosci. 2015 Apr 15;6(4):646-57. [Content Brief]
[2]. V Blair Journigan, et al. Probing ligand recognition of the opioid pan antagonist AT-076 at nociceptin, kappa, mu, and delta opioid receptors through structure-activity relationships. Sci Rep. 2017 Oct 16;7(1):13255. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AT-076 Related Classifications
HY-106732 Related Classifications
Powered by Bioz