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Referencia número: HY-173022

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BDM_92499

BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC₅₀ of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC₅₀ values of 0.46 μM and 4.2 μM, respectively.

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Fòrmula: C₂₅H₃₀N₄O₅
Peso molecular:466.53

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BDM_92499 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC₅₀ of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC₅₀ values of 0.46 μM and 4.2 μM, respectively^[1].

Ver todos los productos específicos de isoformas Aminopeptidase :

CD13
LTA4H

Chemical Information

Peso molecular 466.53
Fòrmula C₂₅H₃₀N₄O₅
SMILES

NC([C@@H](NC(C(CC(C)C)C(NO)=O)=O)CC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C21)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ben He, et al. Discovery of New Nanomolar Selective IRAP Inhibitors. J Med Chem. 2025 Feb 27;68(4):4168-4195. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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BDM_92499

Ver todos los productos específicos de isoformas Aminopeptidase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

BDM_92499 Related Classifications

HY-173022 Related Classifications