BTCy
BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm).
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- Fòrmula: C28H25BrN2OS2
- Peso molecular:549.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
BTCy (0-50 μM; 24 h) has low cytotoxicity and is biocompatible for living cells[1].
BTCy exhibits good fluorescence stability and is able to detect the polarity change selectively[1].
BTCy (10 μM) stains HeLa and HepG2 cells. The cell plasma membrane is specifically and strongly lit up after being stained for 0.5–5 h. The fluorescence intensity of BTCy on the cell plasma membrane shows slight reduction after 2 h[1].
BTCy (0.1-10 μM; 30 min) stain shows specific fluorescence on the cell plasma membrane even at a low concentration at 100 nM in HeLa cells[1].
BTCy (0.1-10 μM; 30 min) can be used for monitoring cell plasma membrane polarity variation during the ferroptosis process[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 549.54
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Fòrmula C28H25BrN2OS2
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SMILES
CCN1C2=C(S/C1=C\C=C3C=CC(C(/C=C/C4=[N+](C5=C(S4)C=CC=C5)CC)=C/3)=O)C=CC=C2.[Br-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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