Cetzole
Cetzole (Compound 1) is a ferroptosis inducer that induces cell death through ROS accumulation. The CC50 values of Cetzole for NCI-H522, NCI-H522 GFP-SCL7A11 #8, NCI-H522 RV-GFP, HT-1080, NARF2, and MDA-MB-231 are 2.56, 10.31, 2.71, 3.07, 14.9, and 6.28 μM, respectively. Cetzole holds potential for research in the field of cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3043764-86-6
- Fòrmula: C11H11NOS
- Peso molecular:205.28
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | CC50 |
3.07 μM
Compound: 1
|
Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| MDA-MB-231 | CC50 |
6.28 μM
Compound: 1
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| MEF | CC50 |
2.41 μM
Compound: 1
|
Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| NCI-H522 | CC50 |
10.31 μM
Compound: 1
|
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| NCI-H522 | CC50 |
2.56 μM
Compound: 1
|
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| NCI-H522 | CC50 |
2.71 μM
Compound: 1
|
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| U2OS | CC50 |
14.9 μM
Compound: 1
|
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
| WI-38 | CC50 |
2.51 μM
Compound: 1
|
Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
|
[PMID: 39264826] |
Chemical Information
-
No. CAS 3043764-86-6
-
Peso molecular 205.28
-
Fòrmula C11H11NOS
-
SMILES
C#CC1=NC(C2=C(C)C(O)CC2)=CS1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cetzole Related Classifications
HY-168093 Related Classifications
Powered by Bioz