CFM-4
Based on 1 Customer Validation
CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.85%
- No. CAS: 331458-02-7
- Fòrmula: C22H16ClN3OS
- Peso molecular:405.90
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-N1462
Atractyloside potassium saltADP/ATP Transport Inhibitor -
HY-15694
SMIP004Apoptosis Inducer -
HY-103257
CHM-1Tubulin Polymerization Inhibitor -
HY-14590
KaempferolEstrogen Receptor α Inhibitor -
HY-110287
ApcinAPC/C Inhibitor -
HY-N1497
PlumbaginAnticancer Agent -
HY-N0164
MatrineAnticancer Agent -
HY-124955
proTAMEAPC Inhibitor -
HY-14590R
Kaempferol (Standard) -
HY-10529
Betulinic acidApoptosis Inducer
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 331458-02-7
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Appearance Solid
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Peso molecular 405.90
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Fòrmula C22H16ClN3OS
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Color Light yellow to yellow
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SMILES
O=C1N(CC2=CC=CC=C2Cl)C3=C(C=CC=C3)C14SC(C5=CC=CC=C5)=NN4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (61.59 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4637 mL | 12.3183 mL | 24.6366 mL | 61.5915 mL |
| 5 mM | 0.4927 mL | 2.4637 mL | 4.9273 mL | 12.3183 mL | |
| 10 mM | 0.2464 mL | 1.2318 mL | 2.4637 mL | 6.1592 mL | |
| 15 mM | 0.1642 mL | 0.8212 mL | 1.6424 mL | 4.1061 mL | |
| 20 mM | 0.1232 mL | 0.6159 mL | 1.2318 mL | 3.0796 mL | |
| 25 mM | 0.0985 mL | 0.4927 mL | 0.9855 mL | 2.4637 mL | |
| 30 mM | 0.0821 mL | 0.4106 mL | 0.8212 mL | 2.0531 mL | |
| 40 mM | 0.0616 mL | 0.3080 mL | 0.6159 mL | 1.5398 mL | |
| 50 mM | 0.0493 mL | 0.2464 mL | 0.4927 mL | 1.2318 mL | |
| 60 mM | 0.0411 mL | 0.2053 mL | 0.4106 mL | 1.0265 mL |
CFM-4 Related Classifications
HY-103255 Related Classifications
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