CHL2310
Based on 1 Customer Validation
CHL2310 is the inhibitor for CYP46A1 with an IC50 of 0.11 nM, and a Kd of 0.37 nM. CHL2310 can cross blood-brain barrier. CHL2310 can be used as a PET imaging agent, when labeled with radioactive 18F.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.45%
- Fòrmula: C16H13F4N3O2
- Peso molecular:355.29
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
IC50: CYP46A1 (0.11 nM)
Kd: CYP46A1 (0.37 nM)
Chemical Information
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Appearance Solid
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Peso molecular 355.29
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Fòrmula C16H13F4N3O2
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Color White to off-white
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SMILES
O=C(N1CCC2=C1C=C(C=C2C3=CN=CO3)C(F)(F)F)N4CC(C4)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (281.46 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8146 mL | 14.0730 mL | 28.1460 mL | 70.3651 mL |
| 5 mM | 0.5629 mL | 2.8146 mL | 5.6292 mL | 14.0730 mL | |
| 10 mM | 0.2815 mL | 1.4073 mL | 2.8146 mL | 7.0365 mL | |
| 15 mM | 0.1876 mL | 0.9382 mL | 1.8764 mL | 4.6910 mL | |
| 20 mM | 0.1407 mL | 0.7037 mL | 1.4073 mL | 3.5183 mL | |
| 25 mM | 0.1126 mL | 0.5629 mL | 1.1258 mL | 2.8146 mL | |
| 30 mM | 0.0938 mL | 0.4691 mL | 0.9382 mL | 2.3455 mL | |
| 40 mM | 0.0704 mL | 0.3518 mL | 0.7037 mL | 1.7591 mL | |
| 50 mM | 0.0563 mL | 0.2815 mL | 0.5629 mL | 1.4073 mL | |
| 60 mM | 0.0469 mL | 0.2346 mL | 0.4691 mL | 1.1728 mL | |
| 80 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8796 mL | |
| 100 mM | 0.0281 mL | 0.1407 mL | 0.2815 mL | 0.7037 mL |
CHL2310 Related Classifications
HY-172205 Related Classifications
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