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Referencia número: HY-121293

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CP-944629

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases.

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No. CAS: 668990-94-1
Fòrmula: C₁₉H₁₅F₃N₄O
Peso molecular:372.34

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CP-944629 Chemical Structure

No. CAS: 668990-94-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases^[1].

Ver todos los productos específicos de isoformas p38 MAPK :

Cellular Effect

Cell Line	Type	Value	Description	References
Monocyte	IC₅₀	8.3 nM Compound: 75	Inhibition of LPS-induced TNFalpha production in human monocytes Inhibition of LPS-induced TNFalpha production in human monocytes	[PMID: 16759861]

Chemical Information

No. CAS 668990-94-1
Peso molecular 372.34
Fòrmula C₁₉H₁₅F₃N₄O
SMILES

FC1=C(C=C(C(C2=C(OC=N2)C3=CN4C(C=C3)=NN=C4C(C)(C)C)=C1)F)F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Shashi Nayana, M. R., et al., (2008). CoMFA and docking studies on triazolopyridine oxazole derivatives as p38 MAP kinase inhibitors. European journal of medicinal chemistry, 43(6), 1261–1269. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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