CuFS
CuFS is a reaction-based fluorescent sensor for detecting Cu2+ with zero background fluorescence. CuFS acts as a fluorescence quencher in the absence of Cu2+ and as a fluorescence enhancer in the presence of Cu2+. CuFS can be fabricated into test strips and applied to the detection of Cu2+ in human cancer cells.
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- No. CAS: 1860808-05-4
- Fòrmula: C20H19N5O6S
- Peso molecular:457.46
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Descripciòn
In Vitro
CuFS (10 μM; 30 min at room temperature) shows almost zero background fluorescence in PBS containing 20% THF. After reaction with 22 μM Cu2+, it produces an 811-fold fluorescence enhancement centered at 469 nm. Its detection limit for Cu2+ is 12.3 nM, with a linear response range from 12.3 nM to 2.0 μM[1].
CuFS (0-20 μM; incubated at 37 °C for 30 min) exhibits negligible background fluorescence and induces concentration-dependent fluorescence enhancement in human hepatocellular carcinoma SMMC-7721 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1860808-05-4
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Peso molecular 457.46
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Fòrmula C20H19N5O6S
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SMILES
CCN(C1=CC=C2C=C(C(OC2=C1)=O)C(NNC3=CC=C(C=C3[N+]([O-])=O)[N+]([O-])=O)=S)CC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CuFS Related Classifications
HY-D3206 Related Classifications
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