d-WRL

d-WRL (7.5 μM) potently inhibits planktonic MRSA with an MIC of 7.5 μM, and this activity is completely maintained in the presence of physiological salt concentrations^[1].
d-WRL achieves complete elimination of planktonic S. aureus MRSA within 90 min when used at its MIC of 7.5 μM, exhibiting faster killing kinetics than Vancomycin (HY-B0671)^[1].
d-WRL inhibits 95% of S. aureus (MRSA) biofilm formation at a concentration of 7.5 μM, with an MBIC₅₀ of 7.5 μM^[1].
d-WRL (7.5-100 μM; 4 h) shows minimal hemolysis (<25%) at concentrations up to 50 μM and is nonhemolytic at its MRSA MIC of 7.5 μM when incubated with human red blood cells for 4 h^[1].
d-WRL (2.5-160 μM) is noncytotoxic at biologically active concentrations against HeLa, HEK 293, and HDF mammalian cell lines, with high cell survival retained at concentrations below 40 μM^[1].
d-WRL (7.5 μM; 6 h) is completely stable to trypsin, chymotrypsin, and proteinase K, retaining its full antimicrobial activity against MRSA (MIC 7.5 μM) after 6 h of incubation with the protease cocktail^[1].
d-WRL (7.5 μM; 6 h) is completely stable in human serum for 6 h, retaining its full antimicrobial activity against MRSA (MIC 7.5 μM)^[1].
d-WRL permeabilizes the inner membrane of planktonic MRSA, increasing propidium iodide fluorescence by 87% relative to Triton X-100^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.