country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-N21732

Copy Link Print Information

Dihydrocucurbitacin E

Dihydrocucurbitacin E is a cucurbitacin anticancer agent found in the rhizomes of Begonia nantoensis. Dihydrocucurbitacin E exhibits cytotoxic effects on gastric cancer cells and nasopharyngeal carcinoma cells. Dihydrocucurbitacin E can be used in research on gastric cancer and nasopharyngeal carcinoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 28973-67-3
Fòrmula: C₃₂H₄₆O₈
Peso molecular:558.71

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (288 KB)

Dihydrocucurbitacin E Chemical Structure

No. CAS: 28973-67-3

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
NUGC-3	IC50	8.60 μg/mL	Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay.	14993759
HONE1 cell line	IC50	2.68 μg/mL	Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay.	14993759

In Vitro

Anti-cancer

Dihydrocucurbitacin E (up to 20 μg/mL) is cytotoxic to human NUGC-3 gastric carcinoma and HONE-1 nasopharyngeal carcinoma cells, with IC₅₀ values of 8.60 μg/mL and 2.68 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

No. CAS 28973-67-3
Peso molecular 558.71
Fòrmula C₃₂H₄₆O₈
SMILES

C[C@]12[C@@](C)([C@@]([C@@](C(CCC(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C1)[H])CC(=O)[C@]3(C)[C@]2(CC=C4[C@]3(C=C(O)C(=O)C4(C)C)[H])[H]
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (288 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Wu PL, et al. Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis. Chemical & pharmaceutical bulletin. 2004 Mar;52(3):345-9.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto