Diosbulbin D
Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells.
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- No. CAS: 66756-57-8
- Fòrmula: C19H20O6
- Peso molecular:344.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Diosbulbin D (10-80 μM; 12-72 h) can induce cytotoxicity in human normal liver L-02 cells[1].
Diosbulbin D (40 μM; 24 h) induces morphological changes in L-02 cells[1].
Diosbulbin D (20-80 μM; 12-48 h) induces L-02 cells apoptosis in a time- and concentration-dependent manner[1].
Diosbulbin D (20-80 μM; 24 h) induces activation of caspase 3 in L-02 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L-02 cells
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Concentration:10, 20, 40 and 80 μM
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Incubation Time:12, 24, 48 and 72 h
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Result:Decreased L-02 cells viability in a concentration- and time-dependent manner.
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Cell Line:L-02 cells
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Concentration:20, 40 and 80 μM
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Incubation Time:12, 24 and 48 h
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Result:Induced apoptosis in a time- and concentration-dependent manner.
Chemical Information
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No. CAS 66756-57-8
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Peso molecular 344.36
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Fòrmula C19H20O6
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SMILES
CC12C3C(C(CC1C(OC(C4=COC=C4)C2)=O)=O)C5CC(OC5=O)C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Diosbulbin D Related Classifications
HY-N3765 Related Classifications
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