1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) is an anionic (negatively charged) phospholipid. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is used to prepare lipid microbubbles as ultrasound contrast agents. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol can be used to construct liposomes as vaccine carriers for the treatment of atherosclerosis. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is applicable to the research of drug delivery and diagnostic preparations.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 217939-97-4
- Fòrmula: C42H83O10P
- Peso molecular:779.08
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol forms part of the protein corona of liposomes and mediates the uptake by antigen-presenting cells[1].
When incorporated at a ratio of 60%, 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol enhances the stability of lipid-based microbubble shells, which helps prolong in vivo blood flow imaging duration and reduce hepatic uptake[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 217939-97-4
-
Peso molecular 779.08
-
Fòrmula C42H83O10P
-
SMILES
OCC(O)COP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)(O)=O
-
Synonyms
DSPG
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Benne N, et al. Anionic 1,2-distearoyl-sn-glycero-3-phosphoglycerol (DSPG) liposomes induce antigen-specific regulatory T cells and prevent atherosclerosis in mice. J Control Release. 2018;291:135-146. [Content Brief]
[2]. Maruyama T, et al. Effect of lipid shell composition in DSPG-based microbubbles on blood flow imaging with ultrasonography. Int J Pharm. 2020;590:119886. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol Related Classifications
HY-148601 Related Classifications
Powered by Bioz