EB-0156
EB-0156 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.0479 and less than 0.001 μM, respectively. EB-0156 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0156 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses.
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- No. CAS: 2832824-43-6
- Fòrmula: C21H32N6O7
- Peso molecular:480.51
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Glucosidase[1]
Endoplasmic Reticulum α-Glucosidases I and II inhibitor[1]
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Cell Line
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Type | Value | Description | References |
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| Vero | CC50 |
125.5 μM
Compound: EB-0156
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
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[PMID: 34870992] |
Chemical Information
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No. CAS 2832824-43-6
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Peso molecular 480.51
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Fòrmula C21H32N6O7
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SMILES
O[C@@H]1[C@](O)(C[C@@H]([C@@H]([C@H]1O)O)NCCCCCCNC2=C(C=C(C=C2)N3N=CC=N3)[N+]([O-])=O)CO
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EB-0156 Related Classifications
HY-145274 Related Classifications
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