Enristomig
Based on 1 Customer Validation
Enristomig (ES-101) is a multispecific antibody. Enristomig is both a PD-L1 antagonist and a conditional agonist of 4-1BB. Enristomig can be used for research on PD-L1 expressing tumors.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.447%
- No. CAS: 2539845-73-1
- Peso molecular:101.884 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Isotype
[G1 VH-VH'-h-CH2-CH3]-dimer
Species Reactivity
Human
IC50 & Target
TNFRSF9 & CD274
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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VH-VH'-h-CH2-CH3
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) can bind Enristomig. The EC50 for this effect is 4.611 ng/mL. -
Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Enristomig. The EC50 for this effect is 2.063 ng/mL.
Chemical Information
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No. CAS 2539845-73-1
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Appearance Liquid
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Peso molecular 101.884 kDa
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Color Colorless to light yellow
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SMILES
[Enristomig]
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Synonyms
ES-101; INBRX-105
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
[1]. Enristomig
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)