ENT-C225
Based on 1 Customer Validation
ENT-C225 is an effective activator of TrkB neurotrophin receptor. ENT-C225 has high effect on activating TrkB receptor (TrkBR), and has good physicochemical properties and neuroprotective properties.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.16%
- No. CAS: 2919962-53-9
- Fòrmula: C26H40N4O5
- Peso molecular:488.62
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
ENT-C225 (Compound 10) (1 µM; 24 h) significantly improves NIH-3T3 TrkB cytotoxicity and reduces cell mortality[1].
ENT-C225 (1 µM; 20 min) promotes TrkB receptor phosphorylation in NIH-3T3 TrkB cells and primary astrocytes[1].
ENT-C225 (500 pM-1 µM; 48 h) has significant neuroprotective effect and enhances in a dose-dependent manner. ENT-C225 promoting the accumulation of TAR DNA-binding protein 43 (TDP43) in the neural network and cytoplasm of spinal motor neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2919962-53-9
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Appearance Solid
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Peso molecular 488.62
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Fòrmula C26H40N4O5
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Color White to off-white
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SMILES
O=C(C1=CC(C(NCCO)=O)=CC(C(NCC2CCN(CC2)CC3CCCCC3)=O)=C1)NCCO
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ENT-C225 Related Classifications
HY-152472 Related Classifications
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