Episterol
Episterol is an Ergosterol (HY-N0181) biosynthetic intermediate. Episterol replaces Ergosterol as the major sterol in Saccharomyces cerevisiae Δerg3 mutants, confers resistance to combined lethal and vacuole-disruptive actions of Amphotericin B (HY-B0221) and MC12 (HY-175024).
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- No. CAS: 474-68-0
- Fòrmula: C28H46O
- Peso molecular:398.68
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
Episterol accumulation in Saccharomyces cerevisiae Δerg3 mutant cells eliminates the synergistic antifungal activity between Amphotericin B (HY-B0221) and MC12 (HY-175024), resulting in an indifferent drug interaction with an FIC index of 2.00[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 474-68-0
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Peso molecular 398.68
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Fòrmula C28H46O
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SMILES
C[C@@]12[C@](C=3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](CCC(C(C)C)=C)C)[H])[H]
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Structure Classification
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Initial Source
Saccharomyces cerevisiae
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Episterol Related Classifications
HY-N9464 Related Classifications
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