FJ-5002
FJ-5002 is a telomerase inhibitor with an IC50 of 2 μM. FJ-5002 can induce telomere shortening, increased chromosomal abnormalities, and senescence/crisis-like features in the human leukemia cell line U937. FJ-5002 exhibits antitumor activity and can be used in the study of cancer.
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- No. CAS: 247129-77-7
- Fòrmula: C20H22ClN3OS3
- Peso molecular:452.06
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 247129-77-7
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Peso molecular 452.06
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Fòrmula C20H22ClN3OS3
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SMILES
CC1=CSC(/C=C(N(CC)C/2=O)\SC2=C3SC4=CC=CC=C4N\3C)=[N+]1CC.[Cl-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Guo WZ, et al. Search for novel anti-tumor agents from ridaifens using JFCR39, a panel of human cancer cell lines. Biol Pharm Bull. 2013;36(6):1008-16. [Content Brief]
[2]. Naasani I, et al FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis. Cancer Res. 1999 Aug 15;59(16):4004-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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