GCase modulator-1
Based on 1 Customer Validation
GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC50=2.23 μM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.0%
- No. CAS: 796079-91-9
- Fòrmula: C22H18N4
- Peso molecular:338.41
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Actividad biológica
AC50: 2.23 μM (Glucosidase)[1]
Chemical Information
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No. CAS 796079-91-9
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Appearance Solid
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Peso molecular 338.41
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Fòrmula C22H18N4
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Color Off-white to yellow
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SMILES
C1(C2=NC3=C(C(N4CC5=C(CC4)C=CC=C5)=N2)C=CC=C3)=CN=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
DMSO : 20 mg/mL (59.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9550 mL | 14.7750 mL | 29.5500 mL | 73.8749 mL |
| 5 mM | 0.5910 mL | 2.9550 mL | 5.9100 mL | 14.7750 mL | |
| 10 mM | 0.2955 mL | 1.4775 mL | 2.9550 mL | 7.3875 mL | |
| 15 mM | 0.1970 mL | 0.9850 mL | 1.9700 mL | 4.9250 mL | |
| 20 mM | 0.1477 mL | 0.7387 mL | 1.4775 mL | 3.6937 mL | |
| 25 mM | 0.1182 mL | 0.5910 mL | 1.1820 mL | 2.9550 mL | |
| 30 mM | 0.0985 mL | 0.4925 mL | 0.9850 mL | 2.4625 mL | |
| 40 mM | 0.0739 mL | 0.3694 mL | 0.7387 mL | 1.8469 mL | |
| 50 mM | 0.0591 mL | 0.2955 mL | 0.5910 mL | 1.4775 mL |