Halobetasol
Based on 1 Customer Validation
Halobetasol (Ulobetasol) is a corticosteroid. Halobetasol can be used for research of severe localized psoriasis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.11%
- No. CAS: 98651-66-2
- Fòrmula: C22H27ClF2O4
- Peso molecular:428.90
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
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Cell Line:HaCaT, THP-1
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Concentration:0.05-12.85 μM
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Incubation Time:24 h
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Result:Affected decreasing the viability in both cell lines up to 50% corresponding to dilution 1/20.
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Animal Model:New Zealand male albino rabbits[2]
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Dosage:0.5 ml
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Administration:Intradermal injection
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Result:Generated blisters were approximately 35% smaller.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 98651-66-2
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Appearance Solid
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Peso molecular 428.90
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Fòrmula C22H27ClF2O4
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Color White to off-white
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SMILES
C[C@@]12[C@](O)([C@H](C[C@]1([C@@]3(C[C@@H](C4=CC(C=C[C@@]4([C@]3([C@H](C2)O)F)C)=O)F)[H])[H])C)C(CCl)=O
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Synonyms
Ulobetasol
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 250 mg/mL (582.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3315 mL | 11.6577 mL | 23.3155 mL | 58.2886 mL |
| 5 mM | 0.4663 mL | 2.3315 mL | 4.6631 mL | 11.6577 mL | |
| 10 mM | 0.2332 mL | 1.1658 mL | 2.3315 mL | 5.8289 mL | |
| 15 mM | 0.1554 mL | 0.7772 mL | 1.5544 mL | 3.8859 mL | |
| 20 mM | 0.1166 mL | 0.5829 mL | 1.1658 mL | 2.9144 mL | |
| 25 mM | 0.0933 mL | 0.4663 mL | 0.9326 mL | 2.3315 mL | |
| 30 mM | 0.0777 mL | 0.3886 mL | 0.7772 mL | 1.9430 mL | |
| 40 mM | 0.0583 mL | 0.2914 mL | 0.5829 mL | 1.4572 mL | |
| 50 mM | 0.0466 mL | 0.2332 mL | 0.4663 mL | 1.1658 mL | |
| 60 mM | 0.0389 mL | 0.1943 mL | 0.3886 mL | 0.9715 mL | |
| 80 mM | 0.0291 mL | 0.1457 mL | 0.2914 mL | 0.7286 mL | |
| 100 mM | 0.0233 mL | 0.1166 mL | 0.2332 mL | 0.5829 mL |