HUHS2002

HUHS2002 is a free fatty acid derivative with the ability to enhance α7 cholinergic receptor activity. HUHS2002 enhances whole-cell membrane currents of α7 ACh receptors expressed in Xenopus oocytes in a concentration-dependent manner. The effects of HUHS2002 were blocked in the presence of the Ca2 /calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93. HUHS2002 activated CaMKII in cultured rodent hippocampal neurons, and this activation was abolished by KN-93. HUHS2002 also partially inhibited the activity of protein phosphatase 1 (PP1) in a cell-free PP1 activity assay.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • No. CAS: 1393102-59-4
  • Fòrmula: C17H24O3
  • Peso molecular:276.37
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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