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Referencia número: HY-133311

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Hydroxy-PEG8-CH2-Boc

(Synonyms: HO-PEG8-CH2COOtBu)

Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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No. CAS: 2869101-36-8
Fòrmula: C₂₂H₄₄O₁₁
Peso molecular:484.58

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Hydroxy-PEG8-CH2-Boc Chemical Structure

No. CAS: 2869101-36-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

Ver todos los productos específicos de isoformas PROTAC Linkers :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2869101-36-8
Peso molecular 484.58
Fòrmula C₂₂H₄₄O₁₁
SMILES

O=C(COCCOCCOCCOCCOCCOCCOCCOCCO)OC(C)(C)C
Synonyms

HO-PEG8-CH2COOtBu
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Hydroxy-PEG8-CH2-Boc

Ver todos los productos específicos de isoformas PROTAC Linkers

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Hydroxy-PEG8-CH2-Boc Related Classifications

HY-133311 Related Classifications