JGB-1-155
JGB-1-155 is a positive allosteric modulators (N-PAMs), which enhances the activity of nicotinamide phosphoribosyltransferase NAMPT with EC50 of 3.29 μM. JGB-1-155 counteracts the oxidative stress, through upregulating the NAD+ in THP-1 human monocytes. JGB-1-155 attenuates TNFα-induced ROS in HT-22 cells .
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- No. CAS: 3011930-28-9
- Fòrmula: C26H38N2O3
- Peso molecular:426.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
EC50: NAMPT (3.29 μM)
Chemical Information
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No. CAS 3011930-28-9
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Peso molecular 426.59
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Fòrmula C26H38N2O3
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SMILES
O=C(N(CCC1(C(C)C)CCOC(C)(C1)C)CC2=CC=C(N(C)C)C=C2)C3=CC=CO3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)