L 748780
L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC50 values of 0.5 μM and > 100 μM for COX-2 and COX-1, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 168086-64-4
- Fòrmula: C19H14Cl3NO4
- Peso molecular:426.68
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
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COX-2 0.5 μM (IC50) |
COX-1 > 100 μM (IC50) |
Chemical Information
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No. CAS 168086-64-4
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Peso molecular 426.68
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Fòrmula C19H14Cl3NO4
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SMILES
O=C(CC1=C(C)N(C(C2=C(Cl)C=C(Cl)C=C2Cl)=O)C3=C1C=C(C=C3)OC)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)