Lysicamine
Based on 1 Customer Validation
Lysicamine, a natural compound, possesses antibacterial, anticancer and anti-inflammation activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.34%
- No. CAS: 15444-20-9
- Fòrmula: C18H13NO3
- Peso molecular:291.30
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>40 μM
Compound: 4K
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35092899] |
| HepG2 | IC50 |
6.2 μg/mL
Compound: 7
|
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
|
[PMID: 11374955] |
| HepG2 2.2.15 | IC50 |
2.4 μg/mL
Compound: 7
|
Cytotoxicity against human HepG2(2.2.15) cells by MTT assay
Cytotoxicity against human HepG2(2.2.15) cells by MTT assay
|
[PMID: 11374955] |
| KB | ED50 |
>10 μg/mL
Compound: lysicamine
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
10.1021/np50019a011 |
| MGC-803 | IC50 |
15.8 μM
Compound: 4K
|
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35092899] |
| RAW264.7 | IC50 |
6.4 μM
Compound: 9
|
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
|
[PMID: 33939429] |
| SK-OV-3 | IC50 |
12.1 μM
Compound: 4K
|
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35092899] |
| T-24 | IC50 |
7.3 μM
Compound: 4K
|
Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35092899] |
| Vero | CC50 |
500 μM
Compound: 17
|
Cytotoxicity against african green monkey Vero cells
Cytotoxicity against african green monkey Vero cells
|
[PMID: 9584402] |
| WI-38 | IC50 |
6.7 μM
Compound: 4K
|
Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 35092899] |
Chemical Information
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No. CAS 15444-20-9
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Appearance Solid
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Peso molecular 291.30
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Fòrmula C18H13NO3
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Color Light yellow to yellow
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SMILES
O=C1C2=CC=CC=C2C3=C(OC)C(OC)=CC4=CC=NC1=C43
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)