Maplirpacept
Based on 1 Customer Validation
Maplirpacept (TTI-622; PF-07901801) is a fusion protein consisting of the CD47-binding domain of human SIRPα linked to the Fc region of human IgG4. Maplirpacept enhances phagocytosis by blocking CD47.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.73%
- No. CAS: 2631667-06-4
- Peso molecular:77.129 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Fusion-SIRPA-IGHG4 Fc
Human
CD47
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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FPIA_[PROTEIN]2-FC
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Immobilized CD47 Protein, Human (HEK293, HY-P72917) can bind Maplirpacept. The EC50 for this effect is 74.77 ng/mL.
Chemical Information
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No. CAS 2631667-06-4
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Appearance Liquid
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Peso molecular 77.129 kDa
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Color Colorless to light yellow
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Synonyms
TTI-622; PF-07901801
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)