MeThPmR
MeThPmR, a ribonucleoside derivative, is a potent and selective human nucleoside transporter 1 (hCNT1) inhibitor (Ki/sub> = 0.16-0.69 μM). MeThPmR exhibit weak inhibitory activity on hCNT2 (IC50 = 360 μM) and hCNT3 (Ki = 4.7 μM). MeThPmR can protect cells from the toxicity of nucleoside drugs. MeThPmR can be used for the research of cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1262032-38-1
- Fòrmula: C12H14N2O5S
- Peso molecular:298.31
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
hCNT1 0.16-0.69 μM (Ki) |
hCNT3 4.7 μM (Ki) |
hCNT2 360 μM (IC50) |
Chemical Information
-
No. CAS 1262032-38-1
-
Peso molecular 298.31
-
Fòrmula C12H14N2O5S
-
SMILES
O=C1N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=C(C=C(C)S3)C3=N1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)