country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-N21573

Copy Link Print Information

Milliamine A

Milliamine A is an alkaloid ingenol ester derivative and a toxic substance that can be isolated from the dried roots of Euphorbia millii Ch. des Moulins. Milliamine A induces respiratory arrest caused by circulatory system damage, ptosis, diarrhea, weakened respiration, decreased body temperature, tremors, dyspnea, clonic-tonic convulsions, hemorrhage, and congestion of the lungs and spleen in mice.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 34391-10-1
Fòrmula: C₄₅H₄₉N₃O₁₀
Peso molecular:791.88

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Milliamine A Chemical Structure

No. CAS: 34391-10-1

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vivo

Milliamine A (Compound 1) (270-2025 μg/kg; i.p.; single administration) exhibits high acute toxicity in male ICR-SLC mice, with an i.p. LD₅₀ of 0.642 mg/kg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

ICR-SLC (male)^[1]
Dosage:

270 μg/kg, 400 μg/kg, 600 μg/kg, 900 μg/kg, 1350 μg/kg, 2025 μg/kg
Administration:

i.p.; single injection
Result:

Exhibited an LD₅₀ of 642 μg/kg (0.642 mg/kg).
Resulted in 0/5 mortality at 270 μg/kg.
Resulted in 1/5 mortality at 400 μg/kg.
Resulted in 1/5 mortality at 600 μg/kg.
Resulted in 5/5 mortality at 900 μg/kg.
Resulted in 4/5 mortality at 1350 μg/kg.
Resulted in 5/5 mortality at 2025 μg/kg.

Chemical Information

No. CAS 34391-10-1
Peso molecular 791.88
Fòrmula C₄₅H₄₉N₃O₁₀
SMILES

O=C(O[C@H]1C(C)=C[C@]23[C@]1(O)[C@H](O)C(COC(C)=O)=C[C@@](C3=O)([H])[C@@]4([H])[C@@](C4(C)C)([H])C[C@H]2C)C5=CC=CC=C5NC(C6=CC=CC(O)=C6NC(C7=CC=CC=C7N(C)C)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Uemura, Daisuke, and Yoshimasa Hirata. The isolation and structure of toxic principles, milliamines A, B, and C, from Euphorbia Millii. Bulletin of the Chemical Society of Japan 50, no. 8 (1977): 2005-2009.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto