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United States

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Referencia número: HY-163193

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MJO445

MJO445 (Compound 7) is a ATG4B inhibitor, which inhibits the autophagy of glioblastoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1968-56-5
Fòrmula: C₁₅H₁₁N₃S
Peso molecular:265.33

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

MJO445 Chemical Structure

No. CAS: 1968-56-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

MJO445 (Compound 7) is a ATG4B inhibitor, which inhibits the autophagy of glioblastoma^[1].

Chemical Information

No. CAS 1968-56-5
Peso molecular 265.33
Fòrmula C₁₅H₁₁N₃S
SMILES

S=C(C1=NC2=C(C=C1)C=CC=C2)NC3=NC=CC=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kim DR, et al. Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma. Pharmacology & Translational Science. 2024 Jan 16.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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