MK-4882
MK-4882 is an HCV NS5A inhibitor with activity in reducing viral load in a chimpanzee model of HCV infection, but with issues of viral breakthrough, prompting the development of compounds with greater potency against more genotypes and NS5A resistance mutations.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1246470-32-5
- Fòrmula: C42H50N8O7
- Peso molecular:778.90
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
7 μM
Compound: MK-4882
|
Cytotoxicity in human HuH7 replicon cells by MTS assay
Cytotoxicity in human HuH7 replicon cells by MTS assay
|
[PMID: 29653894] |
Chemical Information
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No. CAS 1246470-32-5
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Peso molecular 778.90
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Fòrmula C42H50N8O7
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SMILES
O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C2=NC=C(N2)C3=CC=C(C=C3)C4=CC5=CC(C6=CN=C(N6)[C@H]7N(CCC7)C([C@H](C(C)C)NC(OC)=O)=O)=CC=C5O4)=O)OC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)