ML-10
Based on 1 Customer Validation
ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95.0%
- No. CAS: 1216897-16-3
- Fòrmula: C9H15FO4
- Peso molecular:206.21
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
-
Solvente y solubilidad
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
No. CAS 1216897-16-3
-
Appearance Solid
-
Peso molecular 206.21
-
Fòrmula C9H15FO4
-
Color White to off-white
-
SMILES
O=C(O)C(C)(CCCCCF)C(O)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (484.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
-
Ficha de datos (267 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8494 mL | 24.2471 mL | 48.4943 mL | 121.2356 mL |
| 5 mM | 0.9699 mL | 4.8494 mL | 9.6989 mL | 24.2471 mL | |
| 10 mM | 0.4849 mL | 2.4247 mL | 4.8494 mL | 12.1236 mL | |
| 15 mM | 0.3233 mL | 1.6165 mL | 3.2330 mL | 8.0824 mL | |
| 20 mM | 0.2425 mL | 1.2124 mL | 2.4247 mL | 6.0618 mL | |
| 25 mM | 0.1940 mL | 0.9699 mL | 1.9398 mL | 4.8494 mL | |
| 30 mM | 0.1616 mL | 0.8082 mL | 1.6165 mL | 4.0412 mL | |
| 40 mM | 0.1212 mL | 0.6062 mL | 1.2124 mL | 3.0309 mL | |
| 50 mM | 0.0970 mL | 0.4849 mL | 0.9699 mL | 2.4247 mL | |
| 60 mM | 0.0808 mL | 0.4041 mL | 0.8082 mL | 2.0206 mL | |
| 80 mM | 0.0606 mL | 0.3031 mL | 0.6062 mL | 1.5154 mL | |
| 100 mM | 0.0485 mL | 0.2425 mL | 0.4849 mL | 1.2124 mL |
ML-10 Related Classifications
HY-76573 Related Classifications
Powered by Bioz