Mps-BAY2a
Based on 1 Customer Validation
Mps-BAY2a is a monopolar spindle 1 (MPS1) inhibitor with an IC50 of 1 nM against human MPS1. Mps-BAY2a induces mitotic aberrations and apoptosis in cancer cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.30%
- No. CAS: 1382477-96-4
- Fòrmula: C29H28N6O
- Peso molecular:476.57
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
IC50: 1 nM (human MPS1), 2.6 nM (rat MPS1), 9 nM (mouse MPS1)[1]
Chemical Information
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No. CAS 1382477-96-4
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Appearance Solid
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Peso molecular 476.57
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Fòrmula C29H28N6O
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Color Off-white to light yellow
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SMILES
O=C(C1=CC=C(C2=CN=C3C(NCC(C)C)=NC(C4=C5C=CC=NC5=CC=C4)=CN32)C=C1)NC6CC6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 10 mg/mL (20.98 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0983 mL | 10.4916 mL | 20.9833 mL | 52.4582 mL |
| 5 mM | 0.4197 mL | 2.0983 mL | 4.1967 mL | 10.4916 mL | |
| 10 mM | 0.2098 mL | 1.0492 mL | 2.0983 mL | 5.2458 mL | |
| 15 mM | 0.1399 mL | 0.6994 mL | 1.3989 mL | 3.4972 mL | |
| 20 mM | 0.1049 mL | 0.5246 mL | 1.0492 mL | 2.6229 mL |