NS2359
NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 195875-68-4
- Fòrmula: C16H21Cl2NO
- Peso molecular:314.25
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
NS2359 simultaneously blocks three monoamine transporters and increases the levels of three types of neurotransmitters in the synaptic cleft to regulate mood, cognition and reward pathways.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 195875-68-4
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Peso molecular 314.25
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Fòrmula C16H21Cl2NO
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SMILES
COC[C@@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N([C@]1([H])CC3)C
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Synonyms
GSK372475
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Learned S, et al. Efficacy, safety, and tolerability of a triple reuptake inhibitor GSK372475 in the treatment of patients with major depressive disorder: two randomized, placebo- and active-controlled clinical trials. Journal of psychopharmacology (Oxford, England). 2012 May;26(5):653-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)