ORS-14
ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B+ CD8+ T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia.
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- No. CAS: 1311892-52-0
- Fòrmula: C17H17N5O2
- Peso molecular:323.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
LILRB4 85.2 nM (Kd) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1311892-52-0
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Peso molecular 323.35
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Fòrmula C17H17N5O2
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SMILES
O=C(NCC1=CC=NC(OC2=CC=C(C)C(C)=C2)=C1)C3=CNN=N3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ORS-14 Related Classifications
HY-184689 Related Classifications
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