Osimertinib dimer
Osimertinib dimer is a dimer of Osimertinib (HY-15772). Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.
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- No. CAS: 2564638-97-5
- Fòrmula: C56H67N14O4+
- Peso molecular:1000.22
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 2564638-97-5
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Peso molecular 1000.22
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Fòrmula C56H67N14O4+
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SMILES
O=C(NC1=CC(NC2=NC(C3=CN(C)C4=C3C=CC=C4)=CC=N2)=C(C=C1N(CC[N+](C)(CCC(NC5=CC(NC6=NC(C7=CN(C)C8=C7C=CC=C8)=CC=N6)=C(C=C5N(CCN(C)C)C)OC)=O)C)C)OC)C=C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Osimertinib dimer Related Classifications
HY-174293 Related Classifications
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