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Panitumumab

(Synonyms: ABX-EGF)
2 Cited Publications
Revisión del cliente

Based on 2 publication(s) in Google Scholar

Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer.

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  • Pureza: 99.77%
  • No. CAS: 339177-26-3
  • Peso molecular:144.32 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Panitumumab Chemical Structure
    Panitumumab Chemical Structure
No. CAS: 339177-26-3
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Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized EGFR Protein, Human can bind Panitumumab. The EC50 for this effect is 47.19 ng/mL.

  • 1/16

    Panitumumab has a significant ADCP effect on CHOK1-human EGFR cells in a dose-dependent manner.The EC50 for this effect is 130.4 ng/mL.

  • 1/16

    Panitumumab purchased from MedChemExpress. Usage Cited in: Sci Rep. 2022 Jul 7;12(1):11561. [Abstract]

    Customer Validation
     HeLa cells were pretreated with 100 nM cetuximab (Cmab) or 30 nM panitumumab (Pmab) for 10 min and then stimulated with 20 ng/mL TNF-α for 15 or 60 min. The expression of the indicated proteins was detected by immunoblotting.

  • 1/16

    Panitumumab purchased from MedChemExpress. Usage Cited in: Sci Rep. 2022 Jul 7;12(1):11561. [Abstract]

    Customer Validation
     Panitumumab (100 nM, 25 min) was internalized upon stimulation with TNF-α (20 ng/mL, 15 min) in HeLa cells.

  • Panitumumab Chemical Structure
    1/16
  • Panitumumab
  • Immobilized EGFR Protein, Human can bind Panitumumab. The EC50 for this effect is 47.19 ng/mL.
  • Panitumumab has a significant ADCP effect on CHOK1-human EGFR cells in a dose-dependent manner.The EC50 for this effect is 130.4 ng/mL.