Pleconaril-d4
Pleconaril-d4 is deuterium labeled Pleconaril.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2749329-20-0
- Fòrmula: C18H14D4F3N3O3
- Peso molecular:385.37
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
No. CAS 2749329-20-0
-
Unlabeled Cas 153168-05-9
-
Peso molecular 385.37
-
Fòrmula C18H14D4F3N3O3
-
SMILES
FC(C1=NC(C2=CC(C)=C(OC([2H])([2H])C([2H])([2H])CC3=CC(C)=NO3)C(C)=C2)=NO1)(F)F
-
Synonyms
VP 63843-d4; Win 63843-d4
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96(Pt 3):571-9. [Content Brief]
[3]. Lacroix C, et al. http://www.ncbi.nlm. In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J. 2015 Jul 14;12:106. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)