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Referencia número: HY-14444S

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Plinabulin-d₁

(Synonyms: NPI-2358-d₁)

Plinabulin-d1 is an active compound.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2054938-28-0
Fòrmula: C₁₉H₁₉DN₄O₂
Peso molecular:337.39

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Plinabulin-d₁ Chemical Structure

No. CAS: 2054938-28-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- Aplicación
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Plinabulin-d1 is an active compound.

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.5 nM Compound: MBRI-001	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30910474]
Jurkat	IC₅₀	4.3 nM Compound: 9	Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]
NCI-H1975	IC₅₀	9.3 nM Compound: MBRI-001	Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30910474]
NCI-H446	IC₅₀	22 nM Compound: 9	Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]
NCI-H460	IC₅₀	33.2 nM Compound: 9	Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

No. CAS 2054938-28-0
Unlabeled Cas 714272-27-2
Peso molecular 337.39
Fòrmula C₁₉H₁₉DN₄O₂
SMILES

CC(C)(C)C(N=CN1)=C1/C([2H])=C2C(N/C(C(N/2)=O)=C\C3=CC=CC=C3)=O
Synonyms

NPI-2358-d₁
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
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Plinabulin-d1

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Plinabulin-d1 Related Classifications

HY-14444S Related Classifications

Plinabulin-d₁

Plinabulin-d₁ Related Classifications