Polyvinylimidazole
Based on 1 Customer Validation
Polyvinylimidazole (Vimdemer) is an antibacterial polymer and membrane modifier. Polyvinylimidazole can form anticancer complexes with Cadmium chloride. Polyvinylimidazole disrupts bacterial membrane structures through electrostatic and hydrophobic interactions, inhibits bacterial adhesion and biofilm formation, thereby reducing membrane surface biofouling and enhancing the water flux recovery rate after fouling-cleaning cycles. Polyvinylimidazole exhibits broad-spectrum but selective antibacterial activity, inhibiting fungi and bacteria. Polyvinylimidazole can modify PVDF membranes, and the modified membranes inhibit bacteria in a concentration-dependent manner. Polyvinylimidazole can be used in research related to cancer, fungal and bacterial infections.
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- Pureza : 98.0%
- No. CAS: 25232-42-2
- Fòrmula: (C5H6N2)x
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
Polyvinylimidazole (5-15% w/v) modified membranes inhibit E. coli and S. aureus in a concentration-dependent manner[2].
After loading with polyvinylimidazole (5-15% w/v; 107 CFU/mL bacteria; 3 h filtration; before and after cleaning), the live cell area of E. coli and S. aureus on the membrane surface after dynamic fouling decreases, while the dead cell area increases, with the M15 membrane showing the lowest residual live cell area[2].
Polyvinylimidazole (5-15% w/v; 3 h) modified membranes cause structural disruption of adhered E. coli and S. aureus[2].
Polyvinylimidazole (0.5-2 mg/mL; 1-24 h) kills Kloeckera apiculata and Candida albicans, and inhibits all tested bacteria and fungi in plate count assays[3].
Polyvinylimidazole modifies the PVDF membrane, gradually reducing the pore size, porosity, and roughness while increasing the positive zeta potential[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Kloeckera apiculata, Candida albicans, Escherichia coli, Salmonella enteritidis and Staphylococcus aureus
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Concentration:0.5, 1 and 2 mg/mL
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Incubation Time:1, 12 and 24
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Result:Both types of yeast died completely in 1 mg/mL concentration of this compound during 12-24 h treatments.
Exhibited antimicrobial activity against Escherichia coli, Salmonella enteritidis and Staphylococcus aureus.
Weaker activity was shown againstAspergillius niger and Penicillium roqueforti.
Chemical Information
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No. CAS 25232-42-2
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Appearance Solid
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Fòrmula (C5H6N2)x
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Color White to light yellow
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SMILES
CC(CC)N1C=NC=C1.[n]
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Synonyms
Vimdemer
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Pureza y Documentación
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Ficha de datos (288 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polyvinylimidazole Related Classifications
HY-132848 Related Classifications
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