ProINDY
Based on 1 Customer Validation
ProINDY, a prodrug of INDY (HY-108476), is a DYRK1A and DYRK1B inhibitor. ProINDY effectively recovers Xenopus embryos from head malformation induced by Dyrk1A overexpression.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 719277-30-2
- Fòrmula: C14H15NO3S
- Peso molecular:277.34
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Help & FAQs
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Actividad biológica
In the cultured cells overexpressing Dyrk1A or xDyrk1A, ProINDY inhibits the phosphorylation of Thr212 of the tau-protein. ProINDY also rescues the NFAT pathway in Dyrk1A-overexpressing cells, confirming the identical Dyrk1A-inhibitory effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 719277-30-2
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Appearance Solid
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Peso molecular 277.34
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Fòrmula C14H15NO3S
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SMILES
CC(/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ProINDY Related Classifications
HY-108475 Related Classifications
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