Rexaceract
Rexaceract (Rexaceractum) is a heteroaryl compound that binds to β-glucocerebrosidase. Rexaceract maintains the conformational stability of β-glucocerebrosidase and exhibits activating activity. Rexaceract can be used in the research of nervous system-related diseases such as neurodegenerative diseases with Parkinsonism, epilepsy, and schizophrenia.
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- No. CAS: 2648407-86-5
- Fòrmula: C21H19FN4O
- Peso molecular:362.40
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Rexaceract (Example 71) (6-50 μM; 4-day incubation) binds allosterically to β-glucocerebrosidase in human fibroblasts carrying the L444P mutation, increasing the enzyme activity by 1.2- to 1.7-fold[1].\n
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2648407-86-5
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Peso molecular 362.40
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Fòrmula C21H19FN4O
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SMILES
O=C(C1=NC(NC2=C(F)C=CC=C2)=CC(N)=C1)NC3CC4=C(C3)C=CC=C4
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Synonyms
Rexaceractum
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rexaceract Related Classifications
HY-184093 Related Classifications
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