Scio-323
Scio-323 is an orally available p38 mitogen-activated protein kinase (MAPK) inhibitor with the potential to inhibit chronic inflammatory responses associated with polyethylene particles. Scio-323's oral inhibition pattern had a minimal effect on bone formation. Scio-323 administration inhibited net bone formation after the establishment of a chronic inflammatory response to polyethylene particles. Osteoblast-like activity remained low in all cases of Scio-323 inhibition. Scio-323 failed to improve bone growth in the presence of polyethylene particles.
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- No. CAS: 309913-51-7
- Fòrmula: C27H30FN3O4
- Peso molecular:479.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 309913-51-7
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Peso molecular 479.54
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Fòrmula C27H30FN3O4
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SMILES
O=C(C1=CN(C)C2=C1C=C(C(N3CCC(CC3)CC4=CC=C(C=C4)F)=O)C(OC)=C2)C(N(C)C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Scio-323 Related Classifications
HY-167679 Related Classifications
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