2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Referencia número: HY-19690
No. CAS: 476333-91-2
Synonyms: KUC-7483 hydrochloride
Target:  

Adrenergic Receptor

Áreas de investigación:  

Metabolic Disease Endocrinology

Ritobegron, a prodrug of the active compound, KUC-7322, is a selective β3 -adrenoceptor agonist. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
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Referencia número: HY-N11948
No. CAS: 51771-52-9
Simmondsin, derived from the jojoba plant (Simmondsia chinensis), has been shown to decrease food intake and body weight in rats without any noticeable adverse effects.
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Referencia número: HY-N12158
No. CAS: 71627-22-0
Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis .
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Referencia número: HY-N7709
No. CAS: 85022-68-0
Cinchonain IIb is a proanthocyanidin. Cinchonain IIb has the effect of rational utilization of decreased cardiac function. Cinchonain IIb is isolated from natural hawthorn (Crataegus spp. ) .
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Referencia número: HY-P0251A
No. CAS: 2952825-79-3
Target:  

Neurotensin Receptor

Áreas de investigación:  

Neurological Disease

Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.
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Referencia número: HY-124412S
Paynantheine-d3 is a deuterium labeled Paynantheine. Paynantheine is an alkaloid that can be isolated from Mitragyna speciosa. Paynantheine can decrease alcohol intake in mice .
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Referencia número: HY-135381
No. CAS: 887196-30-7
Target:  

Drug Metabolite

Áreas de investigación:  

Cardiovascular Disease

3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
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Referencia número: HY-136568
No. CAS: 2582755-72-2
Pureza:  98.31%
Target:  

STAT

Áreas de investigación:  

Others

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b .
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Referencia número: HY-136961
No. CAS: 35020-81-6
Synonyms: NK266 orotate
Target:  

Fungal

Áreas de investigación:  

Infection

NK 1971 (NK266 orotate) is a derivative of NK266 and shows potential antifungal activity. NK 1971 may result in decreased motor skills and seizures in animals .
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Referencia número: HY-144752
Synonyms: Cyclic spermine
Target:  

Amyloid-β

Áreas de investigación:  

Neurological Disease

cSPM (Cyclic spermine) is a Aβ42 inhibitor. cSPM could suppress the aggregation of three different peptides, Aβ42, amylin and insulin, and decreases cytotoxicity .
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Referencia número: HY-160433
No. CAS: 364039-56-5
Target:  

TNF Receptor

Áreas de investigación:  

Inflammation/Immunology

TNF-α-IN-12 is a TNF-α inhibitor with IC50 of 0.1 μM. TNF-α-IN-12 can decrease the TNF-α blood levels .
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Referencia número: HY-163848
No. CAS: 3053522-48-5
Target:  

Interleukin Related

Áreas de investigación:  

Inflammation/Immunology

Anti-inflammatory agent 90 (compound (R)-7) demonstrates decreasing of 32 % and 40 % for nitrite and IL-6, respectively in LPS-challenged RAW cells .
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Referencia número: HY-168538
Target:  

Paraptosis

Áreas de investigación:  

Infection

Antitrypanosomal agent 21 (Compound C-1) is a trypanosoma brucei inhibitor. Antitrypanosomal agent 21 decreases the level of D6XM23 in parasite lysates .
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Referencia número: HY-177852
No. CAS: 873556-29-7
Target:  

Bacterial

Áreas de investigación:  

Infection

Anthranilyl-AMSN is a potent PqsA inhibitor, with a Kiapp of 170 nM. Anthranilyl-AMSN decreases HHQ and PQS production. Anthranilyl-AMSN can be used in the research of Pseudomonas aeruginosa infections .
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Referencia número: HY-N3960
No. CAS: 66056-18-6
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity .
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Referencia número: HY-N9516
No. CAS: 517-37-3
Synonyms: TDHC
Category:  

Animal Steroids

Target:  

Endogenous Metabolite

Taurodehydrocholic acid is a biliary cholesterol secretion activator. Taurodehydrocholic acid significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid can be used in the study of cholesterol metabolism .
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Referencia número: HY-N9516A
No. CAS: 57011-24-2
Target:  

Endogenous Metabolite

Áreas de investigación:  

Metabolic Disease

Taurodehydrocholic acid sodium is a biliary cholesterol secretion activator. Taurodehydrocholic acid sodium significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid sodium can be used in the study of cholesterol metabolism .
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Referencia número: HY-W168754
No. CAS: 16296-42-7
Target:  

MHC

Áreas de investigación:  

Others

DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands .
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Referencia número: HY-Z7628
No. CAS: 433289-83-9
Target:  

Drug Intermediate

Áreas de investigación:  

Others

Atorvastatin impurity 2 calcium is an impurity of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
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Referencia número: HY-100987
No. CAS: 14919-37-0
Áreas de investigación:  

Others

Lauroylcarnitine chloride enhances the absorption of salmon calcitonin in rats. Also in determining in situ bioavailability, increased availability of Lucifer yellow and decreased expression of claudin-4 protein in the colon .
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