2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Referencia número: HY-103232
No. CAS: 258282-23-4
Target:  

mGluR

Áreas de investigación:  

Neurological Disease

IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
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Referencia número: HY-107906
No. CAS: 12126-59-9
Target:  

Estrogen Receptor/ERR

Áreas de investigación:  

Endocrinology

Conjugated estrogen sodium is a medication composed of a blend of estrogen hormones, utilized in the treatment of moderate to severe hot flashes, vaginal changes, and various other symptoms associated with menopause or decreased estrogen levels.
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Referencia número: HY-108560A
No. CAS: 54276-24-3
Áreas de investigación:  

Others

15(S)-Fluprostenol is the isomer of (+)-Fluprostenol (HY-108560). (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1) .
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Referencia número: HY-114909
No. CAS: 331839-29-3
Target:  

Parasite

Áreas de investigación:  

Infection

TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1,thereby causing a decrease in the activity of the parasite's myosin motor .
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Referencia número: HY-115429
No. CAS: 115940-48-2
Synonyms: (6R)-Leucovorin calcium; (6R)-Folinic acid calcium
Target:  

Drug Derivative

Áreas de investigación:  

Metabolic Disease

Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
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Referencia número: HY-118470
No. CAS: 5696-15-1
Pureza:  99.87%
Synonyms: Butoxamin hydrochloride
Target:  

Adrenergic Receptor

Áreas de investigación:  

Endocrinology

Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats .
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Referencia número: HY-124501
No. CAS: 1814-64-8
Pureza:  99.24%
Synonyms: p-NH2-PE-TFMPP
Target:  

5-HT Receptor

Áreas de investigación:  

Neurological Disease

LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum .
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Referencia número: HY-124597
No. CAS: 1628343-77-0
Pureza:  95.00%
Target:  

Ceramidase

Áreas de investigación:  

Inflammation/Immunology

ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner .
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Referencia número: HY-135380
No. CAS: 125971-95-1
Pureza:  99.94%
Target:  

Drug Intermediate

Áreas de investigación:  

Cardiovascular Disease

Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
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Referencia número: HY-147784
No. CAS: 2041789-14-2
Target:  

Btk

Áreas de investigación:  

Cancer

HZ-A-005 is a potent, selective, and covalent Bruton’s tyrosine kinase (BTK) inhibitor. HZ-A-005 markedly decreases tumor growth in xenograft mouse models .
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Referencia número: HY-153740
No. CAS: 2498597-94-5
Pureza:  99.37%
Synonyms: ARRY-558
Target:  

SHP2

Áreas de investigación:  

Cancer

PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM. PF-07284892 decreases the expression of pERK .
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Referencia número: HY-168363
No. CAS: 58765-21-2
Synonyms: WE-973
Target:  

GABA Receptor

Áreas de investigación:  

Neurological Disease

Ciclotizolam (WE-973) is a thienotriazolodiazepine with anticonvulsant and anti-aggressive activities. Ciclotizolam binds to benzodiazepine receptors in the central nervous system. Ciclotizolam decreases total sleep time in cats .
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Referencia número: HY-A0171A
No. CAS: 10085-81-1
Synonyms: Ba-30803
Target:  

5-HT Receptor

Áreas de investigación:  

Neurological Disease

Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain .
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Referencia número: HY-P11482
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Inflammation/Immunology

Nesfatin-1 (24-53), mouse/rat is a peptide. Nesfatin-1 (24-53), mouse/rat significantly decreases food intake, inhibits gastroduodenal motility .
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Referencia número: HY-P2052
No. CAS: 140716-14-9
Áreas de investigación:  

Others

AWL 60 is a compound with SP antagonist and weak opioid agonist properties, which can antagonize SP-agonists in vitro and attenuate the decrease in blood pressure caused by SP-agonists in vivo.
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Referencia número: HY-P3973
No. CAS: 929555-19-1
Target:  

Bradykinin Receptor

Áreas de investigación:  

Others

Thrombostatin cont-1 is an analogue of thrombostatin, which is a a bradykinin metabolite. Thrombostatin could decrease platelet activation in the canine carotid artery model of balloon angioplasty (BA) injury .
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Referencia número: HY-W017423
No. CAS: 6485-40-1
(-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae .
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Referencia número: HY-107754
No. CAS: 7647-17-8
Pureza:  99.93%
Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na + transport produced by Alloxan . Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models .
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Referencia número: HY-108560R
No. CAS: 54276-17-4
Áreas de investigación:  

Others

(+)-Fluprostenol (Standard) is the analytical standard of (+)-Fluprostenol. This product is intended for research and analytical applications. (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1) .
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Referencia número: HY-108560S
No. CAS: 2714414-92-1
(+)-Fluprostenol-d4 is the deuterium labeled (+)-Fluprostenol (HY-108560). (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1) .
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